Open Letter to Dr. L. Wittelshoefer

Response to Dr. Edwin Yager's open letter to the editor.

Response to Dr Kintz's letter.

In this letter, the author(s) propose(s) that 'the quantitative findings of zolpidem after a single exposure do not fit in with our daily experience' and that 'Given the risk of misinterpretation of the data of Cui et al., the authors see no reason to support the findings of the Chinese group'. Although markedly different from those reported by Villain et al. (1), the results appear. The method...

Reply to Dr. Yamamoto's letter.

We wish to thank Dr. Yamamoto for his letter,1 regarding our paper ‘Exclusive elemental diet impacts on the gastrointestinal microbiota and improves symptoms in patients with chronic pouchitis’.2 In his letter Dr. Yamamoto outlines the changes in cytokines that his group have identified in patients treated with elemental diet for Crohn's disease who experienced symptomatic benefit with this tre...

Reply to Dr. Kotze's and Dr. Yamamoto's letter.

We appreciate the opportunity to reply to Dr. Kotze's and Dr. Yamamoto's letter1 about our paper “Prevention of postoperative recurrence with azathioprine or infliximab in patients with Crohn's disease: an open-label pilot study”, recently accepted for publication in JCC.2 We agree with the first comment concerning the hypothesis that the use of anti-TNF (tumor necrosis factor)-α before surgery...

Response to Letter by Dr. Cristina Brandolini

We appreciate the interest of Dr. Cristina Brandolini and coworkers in our paper on the audiovestibular loss of a vascular cause. We agree that vascular mechanisms and sensitivity to ischemic damage may differ between the vestibular and cochlear organs. In line with our previous report, they reported that cochlear symptoms, such as hearing loss and tinnitus, may be warning signs of an impending...